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AlgoTx appoints Agathe Nadolny Chief Project Management Officer

Paris, Dec 16th 2021 – AlgoTx is a European Biotech developing ATX01, a non-opioid topical treatment for Peripheral Neuropathic Pain.

Stéphane Thiroloix, CEO, comments : “Project Management is a crucially important and arduous function in an R&D company. We are delighted to welcome such a talented expert as Agathe to the team”.

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Agathe Nadolny, MSc, PMP®, brings to AlgoTx over 20 years of experience in healthcare product management across R&D, manufacturing and strategic planning. She held positions of increasing responsibility at Bio-Rad from 2001 to 2017, eventually joining the Executive Committee as Project Management Office Manager. Prior to joining AlgoTx, Agathe was the New Product Launch Program Manager at French Pharma Mayoly Spindler.

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AlgoTx completes Phase I for peripheral neuropathy program ATX01,…

Paris, Nov 15th 2021

France-based biotechnology company AlgoTx, developer of ATX01, an innovative topical treatment for the pain of peripheral neuropathy, announced today that the ATX01 Phase I trial successfully reached its safety and pharmacokinetics objectives, clearing the way for Phase II development in Chemotherapy-Induced Peripheral Neuropathy (CIPN).

Stéphane Thiroloix, Founder & CEO of AlgoTx, comments: “The outcome of this Phase I trial is an important milestone for AlgoTx. We are delighted that ATX01’s innovative approach and formulation did not raise any safety concern, and its PK profile is consistent with our objectives. We are now busy preparing for the pivotal Phase II CIPN study.”

Over half of cancer patients treated with chemotherapy – over two million patients in the US and Europe – develop CIPN and experience sensory symptoms and pain in the feet and hands:  loss of sensitivity, tingling, burning, cold and intense pain can persist for months to years after treatment. CIPN is a leading cause of modification or interruption of chemotherapy. To this date, no therapeutic approach has offered a satisfactory response for patients and their caregivers, oncologists and pain specialists.

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AlgoTx appoints Prof Jens Ellrich Chief Medical Officer

Paris, Nov 8th 2021 – AlgoTx is a European Biotech developing ATX01, a non-opioid topical treatment for Peripheral Neuropathic Pain.

Stéphane Thiroloix, CEO, comments : “With ATX01 entering Phase II in Chemotherapy-Induced Peripheral Neuropathy and  increasing its span of indications, Jens’s medical depth of expertise and biotech experience are a tremendous addition to the team’s profile”.

Jens Ellrich, MD, PhD, spent 18 years in basic and clinical pain research at University hospitals in Germany and Denmark with a track record of more than 85 publications in peer-review scientific journals. He was full professor at RWTH Aachen University and Aalborg University and received the European Award for Pain Research in 2005.

Since 2010, Jens has served as Chief Medical Officer for the international neuroscience start-ups Cerbomed, EBS Technologies, Precisis, Sapiens, and WISE.

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AlgoTx appoints Edmund Harrigan and Scott Byrd to the…

Paris, 12 April 2021 – Founded in 2018 to design topical treatments for complex pain, AlgoTx is developing ATX01 in Chemotherapy-Induced Peripheral Neuropathy. Following the recent Series A fundraising and just as ATX01 initiates Clinical Development, AlgoTx is strengthening its Board of Directors with the appointment of two high-profile independent members.

Edmund P. Harrigan, M.D. has served as a director of Acadia since November 2015.

Ed served as Senior Vice President of Worldwide Safety and Regulatory for Pfizer Inc. from 2012 to 2015.

Ed’s previous executive leadership roles at Pfizer include Senior Vice President, Head of Worldwide Business Development, Senior Vice President, Head of Worldwide Regulatory Affairs and Quality Assurance, Vice President, Head of Neuroscience and Ophthalmology, Vice President of Clinical Development, Therapeutic Area Head, CNS and Pain.

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ATX01 enters Clinical Development

Paris, Feb 12th 2021. France-based biotechnology company AlgoTx, developers of ATX01, an innovative topical treatment for chemotherapy-induced peripheral neuropathy (CIPN), announced today that ATX01 was administered to healthy volunteers participating in a Phase I study, designed to establish the product’s local and systemic tolerance in humans and ascertain its limited systemic passage. This is ATX01’s first administration in humans.

In November 2020, AlgoTx raised 12M€ in a Series A fundraising led by Bpifrance and Omnes Capital, with a view to developing ATX01 through to Phase II in CIPN. The initiation of this Phase I study is the first step in the timely execution of that plan.

Over half of cancer patients treated with chemotherapy develop CIPN and experience sensory symptoms and pain in the hands and feet:  loss of sensitivity, tingling, burning, cold and intense pain can persist for months to years after treatment. CIPN can prevent patients from walking or using their hands, thus deeply affecting their quality of life.

CIPN is found in over two million patients in the US and Europe, a leading cause for modification or interruption of chemotherapy. To this date, no therapeutic approach has offered a satisfactory response for patients and their caregivers, oncologists and pain specialists.

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AlgoTx Receives Regulatory Approval to Initiate Clinical Development of…

Accueil | Business Wire

PARIS, France, December 14th 2020 (BUSINESS WIRE)

France-based biotechnology company AlgoTx, the developer of an innovative topical treatment for chemotherapy-induced peripheral neuropathy (CIPN), announced today it has received approval from the ethics committee and the regulatory authority in the Czech Republic to initiate a Phase 1 clinical trial with ATX01. The trial, which will explore the pharmacokinetics and safety of ATX01 in healthy volunteers, is due to start in January 2021.

I am thrilled by the entry of ATX01 in clinical development as it represents a great step forward towards providing CIPN patients with a response to the crippling pain they endure.

Stéphane Thiroloix, Founder & CEO of AlgoTx
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AlgoTx raises €12M to take ATX01 into clinical development…

Paris, 24 November 2020 – France-based biotechnology company AlgoTx, the developer of an innovative topical treatment for chemotherapy-induced peripheral neuropathy (CIPN), has raised €12M in a Series A round led by Bpifrance through its InnoBio 2 fund with co-investor Omnes. Existing and new business angel investors, also significantly participated in this financing round. The proceeds will be used to fund the clinical development of its lead candidate ATX01 up to clinical proof of concept.

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AlgoTx in Business Worldwide’s Top 20 Innovative Companies

https://www.prnewswire.com/news-releases/algotherapeutix-named-among-top-innovative-companies-to-watch-in-2020-by-business-worldwide-magazine-301173816.html

LONDON, Nov. 17, 2020 /PRNewswire/ — Paris based biotech company AlgoTx has made it to Business Worldwide Magazine’s list of Top 20 Innovative Companies to Watch in 2020.

The program is a celebration of trailblazing organizations who are changing the game in their respective industries and altering the corporate landscape. From a wide range of sectors, these companies are at the cutting edge of breakthrough technologies, innovation and modernized business structures. Those included in the list have a shared goal of developing revolutionary products and technology that drives scalable business models and disrupts established industries and markets.

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AlgoTx featured in Business Worldwide Magazine

AlgoTx – Developing novel treatments for pain control.

Chemotherapy-Induced Peripheral Neuropathy (CIPN) has always been an iceberg in the ocean of cancer care.  Underestimated and heavily consequential. AlgoTx, an innovative Paris based biotech focused on complex pain may well melt the iceberg. 

Chemotherapy-Induced Peripheral Neuropathy (CIPN) is an underestimated and devastating condition. Experienced by over 60 per cent of patients undergoing chemotherapy treatments, it ranks among the leading causes of chemotherapy modification or interruption, and is a cause of intense pain for patients.

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AlgoTx appoints Etienne Bienfait Fin&Admin Mgr.

As our growth accelerates and we embark on the Series A funding round for the clinical development of ATX01, there could be no better time for Etienne Bienfait to join AlgoTx as Manager of Finance an Administration.

Etienne Bienfait

Etienne holds a degree from the University Technical Institute (IUT) in Saint Nazaire and a Research Master in Management from Brest Business School. He has a strong track record in financial controlling at Covage and Bryan Garnier.

AlgoTx is a French biotech start-up, hosted by the Paris Biotech Santé incubator developing ATX01, a treatment for Chemotherapy-Induced Peripheral Neuropathy.

  • AlgoTherapeutix SAS
  • 49 rue des Nouvelles – 92150 Suresnes
  • Contact : contact@algotx.com

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AlgoTx names Philippe Picaut Chief Scientific Officer

Philippe was previously Sr VP Neurosciences R&D at Ipsen, based in Cambridge (USA). He joins us with a large experience in R&D and business development, in particular in the field of neurology. Philippe is a pharmacist and his qualifications include an MSc in fundamental and applied toxicology, an MSc in anatomopathology, and a diploma of the American Board of Toxicology.

Philippe Picaut

Philippe brings a wealth of expertise as AlgoTx prepares to raise a Series A to launch ATX01 into clinical development for Chemotherapy-Induced Peripheral Neuropathy.

AlgoTx is a French biotech start-up, hosted by the Paris Biotech Santé incubator developing ATX01, a treatment for Chemotherapy-Induced Peripheral Neuropathy.

  • AlgoTherapeutix SAS
  • 49 rue des Nouvelles – 92150 Suresnes
  • Contact : contact@algotx.com
News

Roy Freeman joins AlgoTx’s Scientific Advisory Board.

AlgoTx announced today the appointment of Prof Roy Freeman to its Scientific Advisory Board.

Roy Freeman, MD.

Roy Freeman is Professor of Neurology at the Harvard Medical School and director of the Center for Autonomic and Peripheral Nerve Disorders in the Department of Neurology at Beth Israel Deaconess Medical Center in Boston, Massachusetts. 

His research and clinical interests are the physiology and pathophysiology of the small nerve fibers and the autonomic nervous system. His research encompasses the neurological complications of diabetes; neuropathic pain; the autonomic complications of Parkinson’s disease and multiple system atrophy; biomarkers in neurodegenerative diseases; and the diagnosis and treatment of autonomic and peripheral nervous system disorders. 

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